. 2022 Feb 28;11(5):1330. doi: 10.3390/jcm11051330

Table 4.

Univariate and multivariate analysis for the prediction of the primary clinical endpoint (composite of all-cause death, stroke or rehospitalization due to heart failure) in the entire study population.

Variable	Crude HR	95% CI	p	Adjusted HR	95% CI	p
Age	1.073	1.031–1.122	0.002	1.098	1.041–1.158	<0.001
Male sex	1.205	0.693–2.071	0.525	1.124	0.545–2.317	0.750
LVEF < 50%	1.613	0.814–3.221	0.175	1.701	0.704–4.108	0.237
LAVI	1.021	1.012–1.034	0.002	1.011	0.996–1.027	0.142
Hypertension	2.162	1.014–4.596	0.046	1.811	0.717–4.575	0.208
Diabetes	1.834	0.922–3.661	0.086
Stroke	0.851	0.386–1.885	0.685
Obstructive CAD	1.819	1.054–3.171	0.033	1.589	0.805–3.135	0.181
CKD	3.642	2.016–6.595	<0.001	3.873	1.759–8.530	<0.001
Prior MI	1.568	0.671–3.684	0.300	0.749	0.239–2.342	0.619
CHA₂DS₂-Vasc score	1.154	0.963–1.382	0.141
Use of balloon-expandable device	1.033	0.591–1.817	0.917	0.962	0.471–1.965	0.916
Anticoagulation	1.021	0.565–1.838	0.960	0.381	0.107–1.347	0.134
Any AF	1.809	1.032–3.163	0.038	0.343	0.088–1.341	0.124
SR maintenance	0.292	0.162–0.523	<0.001	0.081	0.018–0.368	0.001

HR and p-value were calculated using Cox regression analysis. p < 0.05 indicates statistical significance. AF = atrial fibrillation; HR = hazard ratio; CI = confidence interval; LVEF = left ventricular ejection fraction; LAVI = left atrial volume index; CAD = coronary artery disease; CKD = chronic kidney disease; MI = myocardial infarction; SR = sinus rhythm.