Table 5.

Advantages and disadvantages of different nanomaterials for breast cancer treatment.

Nanocarrier	Advantages	Disadvantages	Reference
Liposome	Uses for a wide variety of drugs and capable of increasing drug load while reducing unwanted drug activity.	Toxicity is caused by cationic lipids. The mononuclear phagocyte system degrades the nanocarriers quickly.	[56]
Dendrimer	It has higher loading capacity due to a variety of multifunctional surface groups and intracellular cavities, as well as it has high bioavailability.	Rapid clearance, organ accumulation, synthesis variability	[56]
Micelles	Reduction of toxicity and other adverse effects.	Use only for lipophilic drugs, low drug loading capacity	[56,57]
Carbon nanotube	To deliver chemotherapeutic and imaging agents, it must be capable of penetrating and localize at the cellular level.	Potential material toxicity	[57]
Polymeric nanoparticles	These are biocompatible, biodegradable, nontoxic, have a longer blood circulation time, less drug change, are less reactive to enzymatic degradation, and site-targeted administration.	Degradation of the carrier	[58]
Solid lipid nanoparticles (SLNs)	Due to its organic nature, it has a high solubility and bioavailability.
	The kinetics of medication release can be better controlled.	Low drug loading capacities Possibly containing other colloidal structures and complex physical state	[59]
Nanostructured lipid carrier (NLCs)	It is second generation SLNs having high drug loading and entrapment potential.
	Long-term stability, prevent particles from coalescing, low toxicity, biodegradation, drug protection.	Gelation of lipid dispersion Polymorphic transition	[59]
	Biocompatible to a high degree.
	Organic solvents may be avoided since the procedures are water-based.
	Simple to scale-up and sterilize, and they are less costly than other materials.
	Carriers based on polymers or surfactants.
	Improve drug release control and/or target.
	When compared to other NLCs, NLCs provide excellent and greater medication content.
	NLCs may transport both lipophilic and hydrophilic molecules. Biodegradability of the majority of lipids.