Table 2.
Estimation of survival and hospital course parameters regarding ToTT as dependent variable.
| Parameter | β | Lower CI95 | Upper CI95 | p Value | Pbonferroni |
|---|---|---|---|---|---|
| Outcome of death (value: NO) | 0.134 | −0.962 | 1.231 | 0.810 | 1 |
| Acetaminophen | 1.62 | 0.747 | 2.49 | 2.8 × 10−4 | 0.00476 |
| Noradrenaline on day 1 of TTM | −0.411 | −2.209 | 1.387 | 0.654 | 1 |
| Noradrenaline during TTM | 0.253 | −1.987 | 2.492 | 0.825 | 1 |
| Noradrenaline last day of TTM | −7.275 | −13.743 | −0.807 | 0.027 | 0.459 |
| PEEP on day 1 of TTM | −0.165 | −0.428 | 0.098 | 0.219 | 1 |
| PEEP during TTM | −0.143 | −0.482 | 0.196 | 0.408 | 1 |
| PEEP last day of TTM | 0.020 | −0.273 | 0.313 | 0.893 | 1 |
| FiO2 on day 1 of TTM | 0.005 | −0.039 | 0.049 | 0.818 | 1 |
| FiO2 during TTM | 0.011 | −0.039 | 0.061 | 0.663 | 1 |
| FiO2 last day of TTM | −0.020 | −0.103 | 0.064 | 0.646 | 1 |
| MV max during TTM | 0.131 | −0.159 | 0.421 | 0.375 | 1 |
| Sacral pressure sores (value: NO) | 0.159 | −0.928 | 1.245 | 0.775 | 1 |
| GIT bleeding (value: NO) | −0.807 | −2.864 | 1.250 | 0.442 | 1 |
| Erythrocyte transfusion num of bags | −0.122 | −0.360 | 0.116 | 0.316 | 1 |
| Max core body temperature | −1.690 | −3.256 | −0.125 | 0.034 | 0.629 |
| % of time above 39 °C during TTM | 0.025 | −0.044 | 0.094 | 0.479 | 1 |
Legend: TTM: targeted temperature management; PEEP: positive end-expiratory pressure; FiO2: fraction of inspired oxygen; GIT: gastro-intestinal tract; β is calculated for probability of ToTT ≥ 25%.