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. 2022 Feb 22;12(5):735. doi: 10.3390/nano12050735

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Intraocular irritation test of PEG-GO nanosheets. (A) Representative images of scotopic electroretinogram at flash intensity of −20 dB and 0 dB 4 weeks after intravitreal injection of PEG-GO nanosheets. (B) Group data of the amplitude of a-wave and b-wave. Bars show mean ± S.D. (C) Representative immunofluorescence images of the retinal whole mount with z scanning, showing the retinal ganglion cells (green). The cell nuclei were displayed in blue. Scale bars = 50 μm. (D) Representative ultrastructural images showing the retinal ganglion cells layer. Scale bars = 500 nm.