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The workflow of radiomics analysis. (A) The tumor region of interests (ROIs), which were manually segmented by an experienced radiologist from CT images with the lung window and contrast-enhanced mediastinal window, respectively; (B) the high throughput image features were extracted automatically from each ROI and the radiomic signatures were selected from them; (C) Random survival forests (RSFs) models were established for the progression-free survival (PFS) prediction.
