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. 2022 Mar 6;27(5):1721. doi: 10.3390/molecules27051721

Table 1.

Quorum sensing inhibitory activity of psammaplin A (1), bisaprasin (2) and hemifistularin 3 in the P. aeruginosa PAO1 lasB-gfp and rhlA-gfp biosensor strains.

Compound IC50 (μM) % Inhibition (100 μg/mL)
lasB-gfp rhlA-gfp lasB-gfp rhlA-gfp
1 14.02 4.99 85.4% 63.3%
2 3.53 2.41 80.1% 68.9%
Hemifistularin 3 - - 31.4% 49.1%