Table 1.
Quorum sensing inhibitory activity of psammaplin A (1), bisaprasin (2) and hemifistularin 3 in the P. aeruginosa PAO1 lasB-gfp and rhlA-gfp biosensor strains.
Compound | IC50 (μM) | % Inhibition (100 μg/mL) | ||
---|---|---|---|---|
lasB-gfp | rhlA-gfp | lasB-gfp | rhlA-gfp | |
1 | 14.02 | 4.99 | 85.4% | 63.3% |
2 | 3.53 | 2.41 | 80.1% | 68.9% |
Hemifistularin 3 | - | - | 31.4% | 49.1% |