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HPD feeding diminishes triglyceride and glycogen content in the liver, regardless of the presence of proglucagon-derived peptides. Liver (a) triglycerides and (b) glycogen levels in NC-fed control mice (black dots; n = 8), HPD-fed control mice (orange dots; n = 8), NC-fed GCGKO mice (white dots; n = 8), and HPD-fed GCGKO mice (green dots; n = 8) after 1 week of feeding (** p < 0.01, **** p < 0.0001). Data are expressed as mean ± SEM.
