Table 3.
Antiacetylcholinesterase and anti-α-glucosidase activities (IC50 values, µg/mL) of the ethanolic extracts of selected Salvia species, rosmarinic acid, and reference compounds.
| Sample | Acetylcholinesterase Inhibition | α-Glucosidase Inhibition |
|---|---|---|
| S. fruticosa | 287.02 ± 6.94 b | 5291.51 ± 335.08 a |
| S. glutinosa | n.d. | 4496.06 ± 66.36 b |
| S. nemorosa | n.d. | n.d. |
| S. officinalis | 268.45 ± 14.14 b | 4451.85 ± 142.22 b |
| S. pratensis | n.d. | n.d. |
| S. sclarea | n.d | n.d. |
| S. verticillata | 1607.87 ± 15.05 a | n.d. |
| rosmarinic acid | 234.77 ± 14.77 c | 4927.45 ± 324.81 b |
| galantamine | 0.12 ± 0.01 d | - |
| acarbose | - | 1104.76 ± 34.80 c |
The data are expressed as mean values of three independent experiments ± standard deviation. Mean values displaying different letters within each column are significantly different according to Tukey’s multiple comparisons test at a 95% confidence level. n.d.: not determined, -: not tested.