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. 2022 Mar 4;14(5):1078. doi: 10.3390/nu14051078

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structurally related compounds of casuarinin do not promote BrdU incorporation into SCs in vitro. (a) Chemical structures of the ellagitannins (casuarinin, casuarictin, and castalagin) and their derivative (ellagic acid). (b) Effects of the ellagitannins and their derivative (250 nM each) on BrdU incorporation into SCs. BrdU incorporation into SCs is expressed as BrdU⁺ SCs per total SCs and is shown as a fold change compared to the Ctrl. Data represent the mean ± SD of three independent cultures. Significant differences (p < 0.05) relative to the Ctrl are indicated in the figure, and non-significant differences (p > 0.05) are not shown in the figure.