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. 2022 Feb 23;14(5):957. doi: 10.3390/nu14050957

Figure 7.

Figure 7

Apoptosis induction on HepG2 cells. HepG2 cells were treated with various concentrations of a chicory flour decoction (Chic) or D-fructose solution (Fru) (from 0.2% to 3%), and also with chlorogenic acids (CGA) or sesquiterpene lactones (STL) (from 5 µM to 100 µM) for 24 h. Resveratrol at a concentration of 200 µM was used as a positive control and DMEM and DMSO as negative ones. As no significant variations were registered between negative controls, the apoptosis induction in each condition was compared to the DMEM control and expressed as a ratio. Statistical analysis was performed using one-way ANOVA and Dunnett’s multiple comparisons test (**** p < 0.0001; *** p < 0.0005 compared with the DMEM control).