Table 9.
Common nanocomposite hydrogel wound dressings.
Nanocomposites | Hydrogel Resin | Wound Types | Advantages | Challenges | Ref. |
---|---|---|---|---|---|
Silver nanoparticles (AgNPs) | Chitosan hydrogel | Acute wounds | Self-cleaning and antibacterial properties. | Crosslinking and 3D printing | [180,181,182] |
AgNPs | Chitosan and hyaluronic acid | Diabetic foot ulcers | Resisting antibiotic bacteria | Crosslinking and fabrication of the nanomaterial | [183] |
AgNPs | Surface-grafted collagen | Acute wounds | Inhibiting of bacterial growth and increase in membrane water absorption | Agglomeration | [184] |
TiO2 | Collagen | In vivo and in vitro excision wounds. | Accelerate healing | Crosslinking and fabrication of the nanomaterial | [185] |
Nano ZnO | Chitin hydrogel | Acute and chronic wounds | Enhanced swelling, blood clotting and antibacterial effect. Absorbing large volumes wound exudate. Controlled degradation, enhanced blood clotting and excellent platelet activation. |
Fabrication of the nanomaterial | [178] |
Nano ZnO | Nitrocellulose | Hard to cover cut wounds | Flexibility, softness, transparency and conformability. | 3D printing | [186] |
Gelatin oxidized starch nanofibers | Lawsonia inermis (henna) | Treating second degree burn | Enhanced fibroblast attachment, proliferation, collagen secretion and antibacterial activity. | 3D printing | [187] |