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. 2022 Feb 25;14(5):919. doi: 10.3390/polym14050919

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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A hydrocolloid patch covered with ZnO nanoparticles bolsters inflammation and proliferative phases, which is confirmed by immunofluorescence staining. Fluorescent micrographs showing different cytokine staining of tissues growing on the posterior wound after 10 days and the quantitative density gap of the inflammation response of the two groups on day 10. (A) Tumor necrosis factor-alpha, TNF-α. (B) Interleukin 8, IL-8. (C) Interleukin 6, IL-6. (D) Interleukin 1 beta, IL-1β. (E) Cluster of Differentiation 68, CD68. (F) Monocyte chemoattractant protein-1, MCP-1. The quantitative density gap of proliferative response of the two groups on day 10. (G) Alpha smooth muscle actin, α-SMA. (H) Vimentin. Scale bars are 50 µm.