Table 2.
Parameters | Control | LGT 1X | MGT 2X | HGT 5X | HGT 10X |
---|---|---|---|---|---|
GOT (U/L) | 117.9 ± 18.8 a | 101.5 ± 6.8 a | 116.2 ± 15.1 a | 140.8 ± 24.5 ab | 176.3 ± 29.5 b |
GST (U/L) | 27.8 ± 2.8 a | 23.0 ± 1.0 a | 26.6 ± 3.6 a | 44.9 ± 16.6 a | 28.0 ± 2.1 a |
Triglyceride (mg/dL) | 66.8 ± 6.1 a | 90.1 ± 15.5 a | 84.8 ± 7.9 a | 75.2 ± 6.8 a | 80.1 ± 7.2 a |
Total cholesterol (mg/dL) | 153.7 ± 6.4 a | 154.6 ± 5.9 a | 142.7 ± 6.5 a | 151.6 ± 5.4 a | 153.7 ± 8.0 a |
HDL (mg/dL) | 117.7 ± 4.29 a | 120.8 ± 5.63 a | 114.0 ± 5.58 a | 122.5 ± 4.09 a | 123.9 ± 7.24 a |
LDL (mg/dL) | 25.0 ± 2.09 b | 22.1 ± 1.72 ab | 19.8 ± 1.28 a | 20.9 ± 0.98 ab | 19.5 ± 1.42 a |
BUN (mg/dL) | 24.9 ± 0.70 a | 27.3 ± 1.32 ab | 28.6 ± 1.74 bc | 31.0 ± 0.77 c | 25.9 ± 1.55 ab |
Creatinine (mg/dL) | 0.228 ± 0.014 a | 0.225 ± 0.017 a | 0.235 ± 0.022 ab | 0.214 ± 0.014 a | 0.277 ± 0.014 b |
Uric acid (mg/dL) | 2.44 ± 0.20 ab | 3.01 ± 0.22 b | 2.13 ± 0.18 a | 2.00 ± 0.24 a | 2.35 ± 0.24 a |
Glucose (mg/dL) | 131.7 ± 10.8 a | 160.5 ± 5.3 bc | 152.3 ± 6.7 ab | 166.9 ± 11.1 c | 138.9 ± 6.6 ab |
CPK (U/L) | 5789 ± 1495 ab | 3420 ± 490 a | 4762 ± 921 a | 6019 ± 1632 ab | 9168 ± 1841 b |
LDH (U/L) | 1214 ± 193 a | 721 ± 134 a | 810 ± 190 a | 924 ± 259 a | 1012 ± 111 a |
Ammonia (μM/L) | 414 ± 87 a | 485 ± 106 a | 632 ± 132 a | 528 ± 124 a | 645 ± 103 a |
Data are the mean ± SEM for n = 10 mice in each group. Values in the same row with different superscript letters (a, b, and c) differ significantly, p < 0.05.