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. 2022 Feb 22;14(5):933. doi: 10.3390/nu14050933

Table 3.

Characteristics of intervention setting and groups.

Ref. Setting
(Duration)
Exercise Group(s) Control Group
[19] Acute/
Inpatient
(~2–3 wks)
Aerobic exercise training Resistance exercise training No exercise
Mode: treadmill or stationary cycling Mode: Isotonic weight machines
Intensity: 70% of HRpeak Intensity: 70% 1 RM
Duration: 30 min Duration: 5 sets of 10 repetitions
Frequency: 5 d/wk Frequency: 5 d/wk
Other: Supplemental oxygen was titrated to keep SpO2 > 90% (if needed). Training was stopped if dyspnea ≥ 7 on Borg CR10 scale. Each session was individually supervised Other: Upper- and lower-extremity exercises (specific exercises and number not defined). Each session was individually supervised
[20] Hospital-based, outpatient gym
(8 weeks)
Aerobic exercise training Chest physiotherapy twice daily and provided verbal instruction on the benefits of physical activity
Mode: Cycle ergometer
Intensity: HR at ventilatory threshold (determined during exercise test)
Duration: 20–40 min
Frequency: 3 d/wk
Other: HR monitor was worn during aerobic exercise. 10 min warmup on cycle. Each session was individually supervised
Resistance exercise training
Mode: Isotonic weight machines (bench press, shoulder press, leg extension, leg press, leg curl, abdominal crunch, low back extension, arm curl, elbow extension, seated row, and lateral pulldown)
Intensity: Progressive, from 40 to 60% of 5 RM
Duration: 3 circuits of 1 set of 12–15 repetitions of each exercise
Frequency: 3 d/wk (following aerobic exercise session)
[21] Hospital-based, outpatient gym
(8 weeks)
Aerobic exercise Chest physiotherapy twice daily, IMT at 10% of PImax, and provided instruction on the benefits of physical activity
Mode: Cycle ergometer and “active playing” (i.e., running and soccer)
Intensity: HR at ventilatory threshold (determined during exercise test)
Duration: 20–40 min
Frequency: 3 d/wk
Other: HR monitor was worn during aerobic exercise. 10 min warmup on cycle. Each session was individually supervised
Resistance exercise
Mode: isotonic weight machine (leg press, pull down, leg extension, bench press, leg curl, seated row and abdominal crunch)
Intensity: Progressive, beginning at 50% of 5 RM
Duration: 3 circuits of 1 set of 12–15 repetitions of each exercise
Frequency: 3 d/wk (following aerobic exercise)
Inspiratory muscle training
Mode: PowerBreathe threshold loading device
Intensity: 40–50% of PImax.
Duration: 30 breaths
Frequency: twice daily, 6–7 d/wk
Other: One IMT session was performed during the 3 d/wk supervised sessions; the remaining IMT sessions were performed independently at home
[18] Home-based with tele-health follow-up every 2 weeks
(3 months)
Aerobic exercise Verbal instructions regarding aerobic exercise which are part of routine outpatient care
Mode: Self-selected per recommendations (e.g., walking, jogging, swimming, dancing skipping rope)
Intensity: No recommendations given
Duration: ≥20 min
Frequency: at least 2 d/wk
Other: Written manual of aerobic and stretching exercises provided

Abbreviations: HR = heart rate; HRpeak = peak HR; SpO2 = pulse oximetry saturation; Borg CR10 = Borg category ratio 10 scale; 1 RM = 1 repetition maximum; 5 RM = 5 repetition maximum; PImax = maximal inspiratory pressure; IMT = inspiratory muscle training.