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. 2022 Feb 28;18(2):e1010092. doi: 10.1371/journal.pgen.1010092

Fig 6. The regulation of MN subtype markers by Hox genes.

Fig 6

(A) The loss of glr-4, itr-1, and mig-13 expression in DA9 and the loss of mig-13 expression in VA12 in egl-5(u202) mutants. glr-4 and mig-13 expression were restored in lin-39(n1760) egl-5(n945) and mab-5(e1239) egl-5(n945) double mutants, respectively. (B) The loss of del-1 and flp-18 expression in VA11 in mab-5(gk670) mutants. Ectopic del-1 expression and loss of flp-18 expression in VA12 in egl-5 mutants. Derepression of unc-129 in DA8 and DA9 in mab-5 and egl-5 mutants, respectively. unc-129 expression was also lost in AS11 in mab-5 mutants and derepressed in PDB in egl-5 mutants. (C) ser-2 expression was lost in VD12 and DA8 in mab-5 mutants and derepressed in VD13 in egl-5 mutants. Scale bars = 20 μm in (A-C). (D) Ectopic expression of flp-13 in DD6 in egl-5 mutants.