| Methods |
Blinding of randomisation: can't tell
Blinding of intervention: no
Complete follow‐up: yes
Blinding of outcome measurement: no |
| Participants |
Preterm infants appropriate for gestational age, excluded if major congenital abnormality, haemolytic disease, hyaline membrane disease or notable respiratory distress. |
| Interventions |
Treatment (N=8): Nutrient‐enriched ("preterm") cow milk formula with taurine at a concentration of 50 milligrams/litre.
Control (N=7): Same formula without added taurine.
Participants were randomised within the first 48 hours of birth. The milk used was introduced at the commencement of feeds and continued exclusively until 3 months of age. |
| Outcomes |
Urinary taurine excretion, energy balance, nitrogen balance, fat absorption.
Growth during the trial period. |
| Notes |
Setting: Hopital Ste‐Justine and le Centre Hospitalier, Quebec, Canada. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
