| Methods |
Blinding of randomisation: can't tell
Blinding of intervention: no
Complete follow‐up: no
Blinding of outcome measurement: no |
| Participants |
31 infants of between 31 and 36 weeks gestation, birth weight of 2200g or less (appropriate for gestational age).
Setting: Children's Hospital, Helsinki, Finland (late 1970s). |
| Interventions |
Treatment (N=17): Standard ("term") cow milk formula with 38 milligrams/litre of taurine.
Control (N=14): Cow milk formula without added taurine. |
| Outcomes |
Growth, nitrogen balance,bile acid kinetics, fat absorption (35% loss‐to‐follow up for intervention group at 4 months assessment). |
| Notes |
NB. The length and head circumference growth rates data were reported as "per metre at birth". We corrected for this by assuming an average length at birth of 44cm, and average head circumference at birth of 32cm. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
