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. 2022 Feb 23;11:e74773. doi: 10.7554/eLife.74773

Figure 1. The average mammalian and human brain plasma membranes.

Two equilibrated membranes taken from the study of Ingólfsson et al., 2017 were cut into four 30 nm x 30 nm large pieces each. The pie charts show the fraction of lipid subgroups in the inner and outer leaflets of the membranes. CHL, cholesterol; PC, phosphatidylcholine; PE, phosphatidylethanolamine; SM, sphingomyelin; GM, gangliosides; PS, phosphatidylserine; FS, fully saturated lipids; MU, monounsaturated lipids; PU, polyunsaturated lipids. Figure inspired by Ingólfsson et al., 2017.

Figure 1.

Figure 1—figure supplement 1. Fraction of different lipidsin the inner and outer membrane leaflets.

Figure 1—figure supplement 1.

Lipids are separated based on both their headgroup architecture and tail saturation. Cholesterol is not included in the graphs. Graphs on the left and right, respectively, correspond to average plasma membrane (APM) and brain plasma membrane (BPM).