Table 4. Methylation quantitative trait loci (mQTL) associated with SoC-CpGs and controls.

CpG set	Number of CpGs with mQTL	Number of mQTL (cis/trans)	Median number of mQTL per CpG (IQR)	Methylation variance explained*
SoC-CpGs	130 (50%)	2771 (2549/222)	6 (2–30)	0.09 (0.08–0.15)
Matched controls	201 (78%)	7886 (7417/469)	15 (4–50)	0.09 (0.06–0.21)
Random controls	50 (19%)	1512 (1476/36)	7 (2–35)	0.1 (0.08–0.18)

^*delta adjusted R² (see Materials and methods); IQR: inter-quartile range.