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. 2022 Feb 24;12:775132. doi: 10.3389/fonc.2022.775132

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Copyright © 2022 Cui, Xin, Li, Deng and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Butorphanol regulates the proliferation and migration of osteosarcoma in a piRNA hsa_piR_006613-dependent manner. (A) CCK-8 assay of the viability of MG63 cells treated with butorphanol and hsa_piRNA_006613 inhibitors. (B) CCK-8 assay of the viability of U2OS cells treated with butorphanol and hsa_piRNA_006613 inhibitors. (C) Transwell assay of the migration of U2OS and MG63 cells treated with butorphanol and hsa_piRNA_006613 inhibitors. ** indicates p<0.01.