Table 1. Calculation of ALDEN Score [4] for Each Drug Recently or Chronically Administrated.

Drug	ALDEN score
	Causal link	Total ALDEN score	Type of drug	Dechallenge	Prechallenge/rechallenge	Drug present in the body on index day	Delay from initial drug component intake to onset of reaction
Paracetamol	Very unlikely	-2	Associated: 2 Drug with definite but lower risk	Negative: -2 Drug continued without harm	Negative: -2 Exposure without reaction	Excluded: -3 Drug stopped	Suggestive: +3 From 5 to 28 days
Sodium enoxaparin	Very unlikely	-5	Not suspected: -1 No evidence of association	Negative: -2 Drug continued without harm	Negative: -2 Exposure without reaction	Excluded: -3 Drug stopped	Suggestive: +3 From 5 to 28 days
Ipratropium bromide	Very unlikely	-3	Not suspected: -1 No evidence of association	Neutral: 0 Drug stopped or unknown	Negative: -2 Exposure without reaction	Excluded: -3 Drug stopped	Suggestive: +3 From 5 to 28 days
Dexamethasone	Very unlikely	-1	Not suspected: -1 No evidence of association	Neutral: 0 Drug stopped or unknown	Not done/unknown: 0 No known previous exposure	Excluded: -3 Drug stopped	Suggestive: +3 From 5 to 28 days
Telmisartan	Very unlikely	-3	Unknown: 0	Neutral: 0 Drug stopped (or unknown)	Negative: -2 Exposure without reaction	Definite: 0 Drug continued	Unlikely: -1 > 56 days