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Down-regulation of miR-665 reduced LPS-induced kidney damage and improved kidney function in vivo. ((a)∼(c)) The contents of serum Cr, serum BUN and urine NAG were detected using commercial kits (“∗”P < 0.05 vs. sham, “#”P < 0.05 vs. LPS + NC, n = 6). (d) Typical HE staining of kidney tissues (400×). (e) The expression of Kim1 was detected using Western blot (“∗”P < 0.05 vs. sham, “#”P < 0.05 vs. LPS + NC, n = 3).
