Table 1.
Baseline Characteristics by Treatment Allocation.
Baseline Characteristics | Lower Dose (n = 64) |
Higher Dose (n = 65) |
Total (N = 129) |
---|---|---|---|
Mean age (SD) | 51.14 (9.40) | 50.02 (12.65) | 50.58 (11.13) |
Median years with diabetes (IQR) | 8 (4-13) | 8 (4-12) | 8 (4-12) |
Race (N = 128) | |||
White | 34 (54%) | 29 (45%) | 63 (49%) |
Black | 28 (44%) | 34 (52%) | 62 (48%) |
Asian or Pacific Islander | 1 (1.6%) | 1 (1.5%) | 2 (1.6%) |
Arabic | 0 | 1 (1.5%) | 1 (0.8%) |
Hispanic Ethnicity | 11 (17%) | 12 (18%) | 23 (18%) |
Use of anti-depressants (N = 128) | 11 (17%) | 12 (19%) | 23 (18%) |
Season of First Dose (N = 128) | |||
Fall | 12 (19%) | 15 (23%) | 27 (21%) |
Winter | 22 (34%) | 22 (34%) | 44 (34%) |
Spring | 16 (25%) | 17 (27%) | 33 (26%) |
Summer | 14 (22%) | 10 (16%) | 24 (19%) |
Screening Mood Measures | |||
Mean CES-D (SD) | 28.41 (8.39) | 28.72 (8.50) | 28.57 (8.41) |
Mean PHQ-9 (SD) | 11.91 (4.20) | 11.74 (4.29) | 11.82 (4.23) |
Vitamin D Laboratory Values (ng/mL) | |||
Median 25 (OH) D2 (IQR) | 4 (4-4) | 4 (4-4) | 4 (4-4) |
Mean 25 (OH) D3 (SD) | 18.61 (6.66) | 20.63 (6.60) | 19.63 (6.68) |
Mean Total 25 (OH) D (SD) | 20.19 (6.40) | 21.49 (6.52) | 20.84 (6.47) |
Physical and Other Laboratory Measures | |||
Median PTH (IQR) (pg/mL) | 49 (36-69) | 49 (38-59) | 49 (36-64) |
Median calcium (IQR) (mg/dL) | 9.4 (9.2 – 9.7) | 9.4 (9.2-9.6) | 9.4 (9.2-9.6) |
Creatinine (SD) (mg/dL) | 0.74 (0.14) | 0.75 (0.15) | 0.75 (0.14) |
Mean systolic blood pressure (SD) (mmHg) | 128.41 (16.40) | 127.43 (14.96) | 127.91 (15.63) |
Mean diastolic blood pressure (SD) (mmHg) | 71.97 (10.64) | 70.94 (8.75) | 71.45 (9.71) |
Mean body mass index (SD) | 39.10 (8.28) | 37.65 (7.71) | 38.37 (8.00) |
Mean HbA1c (SD) (%) | 7.86 (1.97) | 7.68 (1.69) | 7.77 (1.83) |
Mean fasting glucose (SD) (mg/dL) | 170.47 (68.63) | 152.52 (48.76) | 161.43 (59.90) |
Note. Valid N = 129 unless otherwise indicated. SD = Standard deviation of the mean. IQR = Interquartile range.