Table 4.
Estimated Marginal Means Post-hoc Comparisons
| Comparison | Estimate | SE | df | t-value | p-value |
|---|---|---|---|---|---|
| Within-group Val66Val | |||||
| Val66Val Baseline - Val66Val Post0 | 0.6711 | 0.0706 | 2855.3 | 9.499 | <.0001 |
| Val66Val Baseline - Val66Val Post10 | 0.8394 | 0.0717 | 2855.1 | 11.714 | <.0001 |
| Val66Val Baseline - Val66Val Post20 | 0.5644 | 0.0744 | 2856.4 | 7.582 | <.0001 |
| Val66Val Baseline - Val66Val Post30 | 0.4423 | 0.0743 | 2856.5 | 5.953 | <.0001 |
| Within-group Val66Met | |||||
| Val66Met Baseline - Val66Met Post0 | −0.0479 | 0.0690 | 2858.8 | −0.695 | 0.9995 |
| Val66Met Baseline - Val66Met Post10 | −0.0603 | 0.0685 | 2858.8 | −0.880 | 0.9970 |
| Val66Met Baseline - Val66Met Post20 | 0.0521 | 0.0679 | 2858.8 | 0.767 | 0.9990 |
| Val66Met Baseline - Val66Met Post30 | 0.4061 | 0.0650 | 2855.2 | 6.249 | <.0001 |
| Cross-group at same times | |||||
| Val66Val Baseline - Val66Met Baseline | 0.1875 | 0.3442 | 23.2 | 0.545 | 0.5911 |
| Val66Val Post0 - Val66Met Post0 | −0.5315 | 0.3451 | 23.5 | −1.540 | 0.1370 |
| Val66Val Post10 - Val66Met Post10 | −0.7122 | 0.3453 | 23.5 | −2.062 | 0.0504 |
| Val66Val Post20 - Val66Met Post20 | −0.3248 | 0.3459 | 23.7 | −0.939 | 0.3571 |
| Val66Met Post30 - Val66Met Post30 | 0.1514 | 0.3453 | 23.5 | 0.438 | 0.6651 |
Note: Significant differences in MEP amplitudes for Val66Val and Val66Met carriers are highlighted in bold. Estimate = difference in model-estimated MEPs from Baseline to Post-cTBS time points within each BDNF genotype group (Val66Val and Val66Met); SE = standard error of the estimate; df = degrees of freedom. Statistical test results represent Tukey-adjusted values correcting for multiple comparisons within the family of estimates compared.