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. 2022 Mar 10;6(1):e60–e69. doi: 10.1055/a-1760-0105

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Time points (T) of laboratory tests during individual PK-profiling. A preinfusion, t = 15–30 minutes and t = 4 hours sample (left) are performed in all patients. The other time points (right) depend on hemophilia type and brand of factor concentrate. EHL, extended half-life; PK, pharmacokinetic; SHL, standard half-life.