FIG. 1.

Effect of increasing HPMPC dose on normal human keratinocyte (A) and HPV-transformed keratinocyte (B) proliferation. Triplicate plates were seeded with 100 cells each, which were allowed to adhere for 24 h. Cultures were treated three times per week at the indicated doses for 2 weeks. Cells were fixed and stained with Giemsa and proliferation was determined by densitometric analysis of plate surface areas.