Table 1.
Summary of available evidence.
| Therapy | Chronic Antibiotic Dependent Pouchitis | Chronic Antibiotic Refractory Pouchitis | Crohn's Disease Like Pouch Inflammation |
|---|---|---|---|
| Antibiotics | + | – | + |
| Probiotics | ++ | – | – |
| Mesalamine | – | + | – |
| Corticosteroids | – | + | – |
| Adalimumab, Infliximab | – | ++ | + |
| Ustekinumab | – | + | + |
| Vedolizumab | + | ++ | + |
| Tofacitinib | – | + | – |
| Tacrolimus | – | + | – |
| Fecal Microbiota Transplant | – | ++ | – |
+ Indicates supportive evidence is based on cohort studies, ++ indicates supportive evidence is based on randomized controlled trials.
- Indicates no supportive evidence.