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Comparison of Michaelis–Menten and Hill fits for lauric acid ω-1-hydroxylation by CYP168A1
| Model fit | Km/S50 ± SE (μM) | Vmax ± SE (nmol/min/nmol P450) | R2 | Correct fit probability | Difference of AICc |
|---|---|---|---|---|---|
| Michaelis-Menten | 46 ± 5 | 0.14 ± 0.006 | 0.98 | 0.02% | 16.85 |
| Hill | 34 ± 2 (n = 1.5) | 0.12 ± 0.004 | 0.99 | 99.98% |
Abbreviations: AICc, second order Akaike Information Criterion; n, cooperativity value for the substrate binding to the enzyme; SE, standard error.
