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. 2022 Mar 11;25(4):104055. doi: 10.1016/j.isci.2022.104055

Figure 1.

Figure 1

Detection of SARS-CoV-2 using RAPID in a prospective cohort study

RAPID diagnoses COVID-19 in nare swab samples infected with SARS-CoV-2. Ten microliters of the anterior nare sample were deposited on top of the biosensor functionalized with ACE2, which acts as the recognition agent for the viral spike protein. Impedimetric measurements were performed after 2 min of incubation time. Recognition of the SARS-CoV-2 spike protein by ACE2 led to an increased resistance signal measured by electrochemical impedance spectroscopy compared to the control group (i.e., the medium where the collected sample was immersed). This figure was created with BioRender.com.