Table 3.
Annual direct medical cost of treatment and medication for biliary atresia in 2021 US dollars
| (a) Total treatment cost | (b) Medication cost | (a)/(b) | |||||
|---|---|---|---|---|---|---|---|
| n | Mean (SD) | 95% CI | n | Mean (SD) | 95% CI | % | |
| Kasai procedure (age 0–4) | |||||||
| Prediagnosis, outpatient | 163 | 403 (1996) | 94–711 | 163 | 83 (415) | 19 to 148 | 20.7 |
| Prediagnosis, inpatient | 178 | 6444 (9449) | 5046–7842 | 178 | 143 (386) | 86 to 200 | 2.2 |
| KP and inpatient hospitalization | 443 | 42,157 (20,216) | 40,269–44,044 | 443 | 1544 (2031) | 1354 to 1733 | 3.7 |
| Follow-up after KP, outpatient | 428 | 1781 (2487) | 1544–2017 | 428 | 902 (2186) | 694 to 1110 | 50.7 |
| Follow-up after KP, inpatient | 293 | 13,718 (15,190) | 11,971–15,464 | 293 | 672 (1004) | 557 to 788 | 4.9 |
| Liver transplantation (age 0–19) | |||||||
| Pre-transplant checkup, outpatient | 21 | 2080 (4166) | 192–3,985 | 21 | 766 (1664) | 8 to 1523 | 36.7 |
| Pre-transplant checkup, inpatient | 20 | 33,935 (30,148) | 19,826–48,045 | 20 | 1741 (3043) | 317 to 3166 | 5.1 |
| LT and inpatient hospitalization | 24 | 105,334 (34,750) | 90,660–120,007 | 24 | 11,967 (10,268) | 7631 to 16,302 | 11.4 |
| Follow-up after LT, outpatient | 22 | 8051 (5135) | 5774–10,327 | 22 | 5889 (4625) | 3838 to 7940 | 73.2 |
| Follow-up after LT, inpatient | 17 | 17,408 (25,441) | 4328–30,489 | 17 | 4963 (15,158) | − 2831 to 12,757 | 28.5 |
SD standard deviation, CI confidence interval, IQR interquartile range, KP Kasai procedure, LT liver transplantation