TABLE 1.
Nomenclature and properties of HSPBs. The table lists HSPBs, their alternative names and properties. The molecular weight (MW), aminoacidic length (AA) and oligomerization propensity are reported. The presence of the SRLFDQxFG and the I/V-X-I/V motifs are reported. NTD and CTD refer to the N and C-terminal domains, respectively; N/A means not assessed.
| HUGO name | Alternative names | MW (kDa) | AA | SRLFDQxFG motif | I/V-X-I/V | Assemblies |
|---|---|---|---|---|---|---|
| HSPB1 | HSP27; HSP28 | 22,783 | 205 | + | CTD | Oligomers |
| HSPB2 | MKBP | 20,233 | 182 | − | CTD | Small oligomers |
| HSPB3 | HSPL27 | 16,966 | 150 | − | NTD | Small oligomers |
| HSPB4 | αA-Crystallin; CRYAA | 19,909 | 173 | + | NTD/CTD | Oligomers |
| HSPB5 | αB-Crystallin; CRYAB | 20,159 | 175 | + | NTD/CTD | Oligomers |
| HSPB6 | HSP20; p20 | 17,136 | 160 | + | NTD | Dimers |
| HSPB7 | cvHSP | 18,611 | 170 | − | — | Dimers |
| HSPB8 | HSP22; H11; E2IG1 | 21,604 | 196 | + | — | Dimers |
| HSPB9 | CT51 | 17,486 | 159 | − | — | N/A |
| HSPB10 | ODF1 | 28,366 | 250 | − | − | N/A |