Skip to main content
. 2022 Feb 25;9:767987. doi: 10.3389/fcvm.2022.767987

Table 2.

Results of the disproportionality analysis for PPI-associated CVEs (total and specific).

Drug N IC IC025 IC975 ROR ROR025 ROR975
PPIs 62,140 −0.37 −0.39 −0.36 0.74 0.74 0.75
Omeprazole 25,713 −0.43 −0.45 −0.41 0.71 0.70 0.72
Lansoprazole 8,846 −0.67 −0.70 −0.63 0.60 0.58 0.61
Pantoprazole 20,653 −0.09 −0.11 −0.06 0.93 0.92 0.95
Rabeprazole 2,250 −0.19 −0.26 −0.12 0.86 0.82 0.90
Ilaprazole 0 −2.89 0.12
Esomeprazole 3,141 −0.14 −0.20 −0.08 0.90 0.86 0.93
Dexlansoprazole 1,537 −1.34 −1.43 −1.26 0.36 0.34 0.38

CVEs, cardiac and vascular events; N, number of records; IC, information components; ROR, reporting odds ratio; IC025/IC975, the lower/upper limit of 95% confidence interval for the IC; PPI, proton pump inhibitors; ROR025/ROR975, the lower/upper limit of 95% confidence interval for the ROR.