Table 2.
Drug | N | IC | IC025 | IC975 | ROR | ROR025 | ROR975 |
---|---|---|---|---|---|---|---|
PPIs | 62,140 | −0.37 | −0.39 | −0.36 | 0.74 | 0.74 | 0.75 |
Omeprazole | 25,713 | −0.43 | −0.45 | −0.41 | 0.71 | 0.70 | 0.72 |
Lansoprazole | 8,846 | −0.67 | −0.70 | −0.63 | 0.60 | 0.58 | 0.61 |
Pantoprazole | 20,653 | −0.09 | −0.11 | −0.06 | 0.93 | 0.92 | 0.95 |
Rabeprazole | 2,250 | −0.19 | −0.26 | −0.12 | 0.86 | 0.82 | 0.90 |
Ilaprazole | 0 | −2.89 | 0.12 | ||||
Esomeprazole | 3,141 | −0.14 | −0.20 | −0.08 | 0.90 | 0.86 | 0.93 |
Dexlansoprazole | 1,537 | −1.34 | −1.43 | −1.26 | 0.36 | 0.34 | 0.38 |
CVEs, cardiac and vascular events; N, number of records; IC, information components; ROR, reporting odds ratio; IC025/IC975, the lower/upper limit of 95% confidence interval for the IC; PPI, proton pump inhibitors; ROR025/ROR975, the lower/upper limit of 95% confidence interval for the ROR.