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. 2022 Mar 10;12:4222. doi: 10.1038/s41598-022-08206-z

Table 6.

Distribution of ICHD3 diagnoses with different mitochondrial genotypes.

Genotype No MO MA/HM CM pMO pMA iETTH fETTH Others Tot
nDNA DGUOK 1 0 0 0 0 0 0 0 0 1
MGME1 1 0 0 0 0 0 0 0 0 1
MICU1 0 0 1 0 0 0 0 0 0 1
OPA1 0 0 0 0 0 0 0 1 0 1
POLG 2 2 0 0 2 0 0 0 1 7
Likely nDNA Multiple deletions 1 2 0 0 2 0 1 0 0 6
mtDNA point mtM 0 2 0 0 0 0 0 0 0 2
MELAS 0 3 1 0 0 0 0 1 1 6
mtDNA deletion Single deletion 3 6 0 0 2 0 2 0 0 13
Total All 8 15 2 0 6 0 3 2 2 38

No no headache, MO migraine without aura, MA migraine with aura, HM hemiplegic migraine, CM chronic migraine, pMO probable migraine without aura, pMA probable migraine with aura, iETTH infrequent tension-type headache, fETTH frequent tension-type headache, DGUOK deoxyguanosine kinase, MGME1 mitochondrial genome maintenance exonuclease 1, MICU1 mitochondrial calcium uptake 1, OPA1 OPA1 mitochondrial dynamin like GTPase, POLG DNA polymerase gamma, mtM other point mtDNA mutations, MELAS mitochondrial encephalopathy, lactic acidosis and stroke-like episodes.