. 2022 Mar 10;12:99. doi: 10.1038/s41398-022-01867-4

Table 2.

Selective behavioral deficits of Notch1^+/− males only in a social novelty recognition behavior, but not in other behavioral paradigms.

RDoC domain construct	Behavior	Test	Result
Arousal/Regulatory systems Arousal	Locomotion	Open field	No difference
Sensorimotor systems	Sensorimotor gating	Prepulse inhibition
Negative valence Potential threat (anxiety)	Anxiety-like	Open field
Negative valence Potential threat (anxiety)	Anxiety-like	Elevated plus maze
Cognitive systems	Object novelty recognition	Novel object recognition
Systems for social processes	Sociability	Three chamber social interaction
Systems for social processes	Social novelty recognition	Three chamber social interaction	Impaired

Significant results are highlighted in bold.