Table 3.
Correlation of JAG1 and NOTCH1 expression with emotional face processing measures in the FEP cohort.
| Group | Sex | Gene | Clinical variable | Correlation coefficient | p-value |
|---|---|---|---|---|---|
| FEP | Male | NOTCH1 | Memory accuracy | −0.395 | 0.293 |
| Memory response time | −0.134 | 0.752 | |||
| Recognition accuracy | −0.019 | 0.960 | |||
| Recognition response time | −0.083 | 0.831 | |||
| JAG1 | Memory accuracy | −0.716 | 0.030 | ||
| Memory response time | 0.686 | 0.060 | |||
| Recognition accuracy | −0.563 | 0.114 | |||
| Recognition response time | 0.664 | 0.051 | |||
| FEP | Female | NOTCH1 | Memory accuracy | −0.057 | 0.904 |
| Memory response time | −0.670 | 0.100 | |||
| Recognition accuracy | −0.239 | 0.606 | |||
| Recognition response time | −0.702 | 0.079 | |||
| JAG1 | Memory accuracy | 0.019 | 0.968 | ||
| Memory response time | −0.609 | 0.147 | |||
| Recognition accuracy | 0.390 | 0.388 | |||
| Recognition response time | −0.314 | 0.493 | |||
| HC | Male | NOTCH1 | Memory accuracy | −0.016 | 0.949 |
| Memory response time | −0.234 | 0.350 | |||
| Recognition accuracy | 0.040 | 0.875 | |||
| Recognition response time | −0.313 | 0.207 | |||
| JAG1 | Memory accuracy | 0.141 | 0.578 | ||
| Memory response time | 0.382 | 0.118 | |||
| Recognition accuracy | 0.060 | 0.813 | |||
| Recognition response time | −0.183 | 0.468 | |||
| HC | Female | NOTCH1 | Memory accuracy | 0.136 | 0.509 |
| Memory response time | −0.122 | 0.554 | |||
| Recognition accuracy | −0.051 | 0.805 | |||
| Recognition response time | 0.277 | 0.171 | |||
| JAG1 | Memory accuracy | −0.152 | 0.460 | ||
| Memory response time | −0.154 | 0.452 | |||
| Recognition accuracy | 0.348 | 0.082 | |||
| Recognition response time | −0.167 | 0.415 |
Significant results are highlighted in bold (p < 0.05).
FEP first episode psychosis, HC healthy controls.