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. 2022 Mar 10;12:3950. doi: 10.1038/s41598-022-07681-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mechanical integrity changes on exposure to amniotic fluid. (a) Representative stress–strain curves for control (0 weeks) and 4, 8, 12 and 16-week patch exposure to amniotic fluid. For each time point, the stress–strain curve of one specimen was chosen randomly out of the five specimens tested. These curves were plotted on the graph to study changes in the mechanical behavior of the patch, i.e. PLA-PCL blend. (b) White arrows indicate presence of necking phenomenon, i.e. stretching of the specimen at the point of fracture. Absence of white arrows indicates brittle fracture.