Table 3.

Four serum markers and CHI3L1 in the control and OSA subgroups.

Variables	Control (n = 20)	OSA (n = 74)
		Mild OSA (n = 15)	Moderate OSA (n = 24)	Severe OSA (n = 35)
HA (ng/ml)	23.62 ± 5.93	33.12 ± 10.6*	34.53 ± 13.2*	35.44 ± 10.7**
PIIINP (ng/ml)	7.384 ± 1.69	7.12 ± 2.28	7.368 ± 2.24	8.32 ± 3.1
CIV (ng/ml)	41.78 ± 8.72	37.41 ± 4.57	39.55 ± 3.46	45.52 ± 2.45*
LN (ng/ml)	27.29 ± 6.39	27.37 ± 7.69	29.12 ± 7.92	30.48 ± 7.4
CHI3L1 (ng/ml)	34.45 (26.7, 41.3)	35.42 (29.42, 41.2)	37.88 (29.9, 51.2)	40.35 (31.9, 54.9)*

HA, hyaluronan; PIIINP, procollagen type III N-terminal peptide; CIV, type IV collagen; LN, laminin; CHI3L1, Chitinase-3-like protein 1.

^*p < 0.05, compared with the control group.

^**p < 0.001, compared with the control group.