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. 2022 Feb 25;16:836116. doi: 10.3389/fncel.2022.836116

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Copyright © 2022 Szlaga, Sambak, Trenk, Gugula, Singleton, Drwiega, Blasiak, Ma, Gundlach and Blasiak.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Synaptic inputs to type I and II NI neurons. (A) Exemplary traces of voltage clamp recordings (holding potential –50 mV) illustrating spontaneous inhibitory (upward deflections) and excitatory (downward deflections) postsynaptic currents in type I and type II NI neurons. (B) Cumulative frequency distribution histograms of the inhibitory (left) and excitatory (right) PSC inter-event intervals (bin size = 20 ms). Insets, comparisons of PSCs frequencies *(p = 0.014), **(p = 0.003), unpaired t-tests. (C) Cumulative frequency distribution histograms of sIPSC and sEPSC amplitudes (bin = 1 pA). Insets, comparisons of PSC amplitudes, **(p = 0.008, unpaired t-test). ePSC, excitatory postsynaptic current; iPSC, inhibitory postsynaptic current.