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HSC inhibits the activation of TAK1 via PIP2. RAW264.7 (A), THP-1 (B) cells treated with HSC for 4 h, and then induced by LPS (1 μg/ml) for 1 h; The collected proteins were immunoprecipitated with PIP2 using magnetic beads, and immunocomplexes were determined by western blotting; ### P < 0.001 compared to control alone group; *** P < 0.001 versus the LPS group, (n=3).
