Table 7.
Description of 11 protein biomarkers involved in embryo development.
| Functional class | Protein name (Gene symbol) | Annotation |
|---|---|---|
| Intermediate filament | Keratin, type I cytoskeletal 47 kDa isoform X2 (KRT12)1 | Expressed in epithelial tissue and participate in forming cytoskeleton |
| Keratin, type I cytoskeletal 15 (KRT15) | ||
| Keratin, type I cytoskeletal 19 (KRT19) | ||
| Keratin 6A isoform X2 (KRT6A) | ||
| Neurodevelopment | L-lactate dehydrogenase B chain (LDHB) | Expressed in embryo glycogen body |
| Neuronal growth regulator 1 precursor (NEGR1) | Promotion neurite growth and development | |
| Blood coagulation | Fibrinogen alpha chain (FGA) | Crucial coagulation proteins in hemostasis and clot formation |
| Fibrinogen beta chain (FGB) | ||
| Fibrinogen gamma chain (FGG) | ||
| Antimicrobial | Alpha-2-macroglobulin (A2M) | Inhibit a broad spectrum of proteases |
| Ovomucin precursor (MUC5B) | Potential effector of innate immunity |
1
Bold items are proteins that are favorable to embryo development when overrepresented.