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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Biochem Pharmacol. 2021 Nov 26;195:114859. doi: 10.1016/j.bcp.2021.114859

Figure 3. CCL5 induces vascular migration dependent on Nox1.

Figure 3.

Effects of CCL5 (100ng/mL, 12h) on Rat Aortic Vascular Smooth Muscle Cells (RASMC) migration analyzed by boyden chamber assay (A). Phalloidin staining (red) in RASMC treated with CCL5 (100ng/mL for 24h) (B); Erk1/2 phosphorylation levels in RASMC treated with CCL5 (100ng/mL for 30min and 60min). Nox1 was inhibited by GKT771 (10uM). N=4–8. White arrows mean changes in F-actin organization. Data are presented as mean ± standard error of the mean (SEM). *P<0.05 vs vehicle; #P<0.05 vs vehicle. #P<0.05 vs CCL5+GKT771.