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. 2022 Feb 25;12:760419. doi: 10.3389/fendo.2021.760419

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Copyright © 2022 Morris, Saboury, Ahlman, Malayeri, Jones, Chen and Millo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) 18F-FCH PET/CT whole body imaging in a patient with severe hyperparathyroidism depicting multiple brown tumors on maximum intensity projection (MIP) images (arrows), coronal CT (left) and fusion PET/CT (right) images depicting parathyroid adenoma (B1), axial (B2) and oblique (B3) CT (left) and fusion PET/CT (right) images depicting brown tumor (arrows), axial CT depicting sclerotic healed brown tumor (B4) following cure of hyperparathyroidism. (C) Comparison of acquisition protocols for 18F-FCH PET/CT showing cases where an earlier <10 min time point had higher uptake compared to a delayed >60min time point (C1, C2), cases where earlier and delayed time points where similar (C3, C4), and cases where the delayed time point had increased uptake (C5, C6). 18F-FCH, 18F-fluorocholine. Reproduced with permission from: (A, B) Zhang-Yin J, Gaujoux S, Delbot T, GauthéM, Talbot JN. 18F-Fluorocholine PET/CT Imaging of Brown Tumors in a Patient With Severe Primary Hyperparathyroidism. Clin Nucl Med. 2019 Dec;44(12):971-974. doi: 0.1097/RLU.0000000000002814. PMID: 31652163. (C) Morland D, Richard C, Godard F, Deguelte S, Delemer B. Temporal Uptake Patterns of 18F-Fluorocholine Among Hyperfunctioning Parathyroid Glands. Clin Nucl Med. 2018 Jul;43(7):504-505. doi: 10.1097/RLU.0000000000002132. PMID: 29762240.