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. 2022 Feb 25;13:835014. doi: 10.3389/fgene.2022.835014

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Copyright © 2022 Sun, Zheng and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of a ZNF protein gene–based signature in osteosarcoma training cohort. (A, B) Lasso regression and multivariable Cox regression analyses were performed to identify genes for the prognostic signature. (C) The coefficients of the seven genes. (D) Risk score distribution. (E) Survival time and survival status of patients in high- and low-risk groups. (F) Kaplan–Meier survival analysis in high- and low-risk groups. (G) Time-dependent ROC curves for 1-, 2-, and 3-year survival.