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. 2022 Feb 25;13:835014. doi: 10.3389/fgene.2022.835014

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Copyright © 2022 Sun, Zheng and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of the ZNF protein gene-based signature in osteosarcoma testing and entire cohorts. (A, B) Risk score distribution of patients in testing and entire cohorts. (C, D) Survival time and survival status of patients in testing and entire cohorts. (E, F) The expression profile of the seven ZNF protein genes in testing and entire cohorts. (G, H) Kaplan–Meier survival analysis of high- and low-risk patients in testing and entire cohorts. (I, J) Time-dependent ROC curves for 1-, 2-, and 3-year survival in testing and entire cohorts.