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. 2022 Feb 25;13:848813. doi: 10.3389/fphar.2022.848813

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Copyright © 2022 Yang, Yv, Ye, Chen, He, Li and Dong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protective effect of ECH against MPTP-induced behavioral dysfunction. (A) The autonomous trajectory map of mice in the open field test. (B) Total distance traveled of mice in the open field test. (C) The number of line crossings of mice in the open field test (D) The residence time of mice in the rotarod test. (E) The average time change of the pole test. N: normal; MPTP: MPTP-induced mice; LE: MPTP + 10 mg/kg/d ECH; ME: MPTP + 20 mg/kg/d ECH; HE: MPTP + 30 mg/kg/d ECH. Values are presented as the mean ± SEM. ^* p < 0.05, ^** p < 0.01.