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. 2022 Feb 25;13:827279. doi: 10.3389/fneur.2022.827279

Table 3.

Logistic regression analysis of different variables and prognosis in training set.

Variables Univariate analysis Multivariate analysis
OR (95% CI) P -value OR (95% CI) P -value
Age ≥60y, n (%) 1.845 (1.251–2.721) 0.002 1.887 (1.205–2.955) 0.006
Male, n (%) 0.600 (0.412–0.874) 0.008 0.687 (0.440–1.071) 0.098
Smoking, n (%) 0.731 (0.486–1.100) 0.133
NIHSS >5 on admission, n (%) 7.542 (5.024–11.320) <0.001 7.200 (4.678–11.081) <0.001
mRS score >1 before stroke, n (%) 8.422 (3.147–22.539) <0.001 4.945 (1.593–15.348) 0.006
Stroke, n (%) 1.820 (1.211–2.734) 0.004 1.866 (1.155–3.015) 0.011
Coronary heart diseases, n (%) 2.089 (1.271–3.435) 0.004 1.448 (0.797–2.630) 0.225
Atrial fibrillation, n (%) 3.530 (1.941–6.418) <0.001 1.853 (0.878–3.910) 0.106
Hypertension, n (%) 1.417 (0.962–2.087) 0.078
Diabetes mellitus, n (%) 1.418 (0.919–2.190) 0.115
Dyslipidemia, n (%) 0.895 (0.492–1.627) 0.895
White blood cell >9.5 × 109 /L, n (%) 1.146 (0.701–1.874) 0.587
TC ≥5.2 mmol/L, n (%) 1.185 (0.750–1.873) 0.466
LDL–C ≥3.61 mmol/L, n (%) 1.257 (0.772–2.045) 0.358
State 1 1 (reference) 1 (reference)
State 2 1.126 (0.618–2.051) 0.699 1.132 (0.581–2.207) 0.715
State 3 1.784 (1.028–3.097) 0.040 1.773 (0.963–3.266) 0.066
State 4 2.460 (1.450–4.173) 0.001 2.224 (1.215–4.072) 0.010

NIHSS, national institute of health stroke scale; mRS, modified rankin scale; TC, total cholesterol; LDL-C, low density lipoprotein-cholesterol; Neutrophils and high-density lipoprotein cholesterol states: State 1: N <4.79 × 109 /L and HDL-C ≥1.08 mmol/L; State 2: N <4.79 × 109 /L and HDL-C <1.08 mmol/L; State 3: N ≥4.79 × 109 /L and HDL-C ≥1.08 mmol/L; State 4: N ≥4.79 × 109 /L and HDL-C <1.08 mmol/L; N, Neutrophil; HDL-C, high-density lipoprotein cholesterol; Multi-factor logistic regression analysis included: age ≥60 y, male, NIHSS>5 on admission, mRS score>1, history of stroke, coronary heart diseases, atrial fibrillation, neutrophils and high-density lipoprotein cholesterol states.