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. 2022 Feb 25;13:855054. doi: 10.3389/fphys.2022.855054

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Copyright © 2022 Reho, Nakagawa, Mouradian, Grobe, Saravia, Burnett, Kwitek, Kirby, Segar, Hodges, Sigmund and Grobe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plethysmography system. Custom built 200 ml mouse plethysmograph for the measurement of ventilatory functions during control and challenge (e.g., hypoxia or hypercapnia) conditions. Chamber is placed above a radiotelemetric receiver antenna to enable simultaneous measurements of blood pressure, electrical potential (e.g., electrocardiogram), core temperature, or other endpoints via previously implanted probes. Chamber is also interfaced with a wireless optogenetic system antenna assembly, to permit simultaneous optogenetic activation/inhibition of cellular functions via previously implanted wireless LED-based stimulators.