Fig. 4.

Phylogenetic tree depicting the Mph macrolide 2'-phosphotransferases predicted in this study. Known ARGs and new gene families of high interest are annotated in the tree and experimentally validated new ARGs are marked by a star. Each leaf is coloured based on the phylum of the identified host(s), whether it was found only in metagenomic data, or if it was discovered in multiple phyla (mobile). The tree scale is displayed at the bottom right of the figure. Additional details, including bootstrap support values, can be found in Fig. S6.