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. 2022 Jan 27;8(1):000770. doi: 10.1099/mgen.0.000770

Table 1.

Summary of predicted macrolide resistance genes and the analysed datasets. Numbers within brackets indicate the number of genomes or metagenomic samples associated with each dataset

Erm

Erm

Mph

Mph

Dataset

Size (nt)

Genes

Families a,b

Genes

Families a,b

Ref.

Genomic

NCBI RefSeq [15,438]

6.21×1010

330

10/21

1107

13/59

[68]

NCBI Assembly [412,184]

1.71×1012

12423

29/314

14033

14/210

[69]

Metagenomic

HMP [757]

4.69×1012

82

7/7

8

1/1

[42]

Human gut 1 [170]

1.93×1011

15

6/5

2

1/1

[44]

Human gut 2 [114]

1.32×1012

14

7/3

2

1/1

[43]

Pig gut [295]

1.74×1012

145

10/9

17

1/0

[45]

Wild baboon gut [48]

1.37×1011

0

0/0

0

0/0

[70]

Wild rhino gut [17]

6.21×1010

0

0/0

0

0/0

[71]

WWTP [70]

4.82×1011

49

6/35

8

4/4

[46]

Pune river [62]

3.91×1011

45

6/33

13

4/7

[47]

Tara oceans [245]

4.89×1012

2

0/2

1

0/1

[72]

Antarctic soil [3]

6.25×109

0

0/0

0

0/0

[73]

Forest soil [36]

1.99×1011

6

1/5

6

3/2

[48]

Oilspill [13]

2.75×1011

0

0/0

0

0/0

[74]

Lake Hazen [8]

2.75×1011

32

0/21

0

0/0

[49]

Amazon river [106]

2.88×1011

0

0/0

0

0/0

[75]

Total

1.67×1013

13143

30/392 c

15197

14/227 c

a, Amino acid identity <70%.

b, Known/new.

c, Non-redundant.

HMP, Human Microbiome Project; WWTP, Wastewater treatment plant.