Table 2.
Comparative analysis of SNPs detected in ATCC 19606(M), ATCC 19606(H) and ATCC 19606(A) genomes
|
Mutation |
Position in ATCC 19606(M) |
Position in ATCC 19606(H) |
Nucleotide change |
Aminoacid change |
Protein length (aa) in ATCC 19606(M)/ ATCC 19606(A)/ ATCC 19606(H) |
Gene designation in ATCC 19606(M)/ ATCC 19606(H) |
Gene designation in ATCC 19606(A) |
Gene product |
Gene designation in ACICU (Protein length) |
|---|---|---|---|---|---|---|---|---|---|
|
|
SNPs between ATCC 19606(M) and ATCC 19606(A) |
||||||||
|
Frameshift |
175 678 |
|
T ->TG |
G80W |
85/513/513 |
GO593_01010/FQU82_02766 |
HTZ92_0804 |
MFS transporter |
DMO12_ 07743 (513) |
|
426 614 |
|
A ->AT |
L235F |
258/548/548 |
GO593_02100/FQU82_02985 |
HTZ92_0587 |
Phospholipid carrier-dependent glycosyltransferase |
DMO12_08688 (548) |
|
|
1 052 567 |
|
G ->GA |
F207I |
222/213/213 |
GO593_04990/FQU82_03557 |
HTZ92_0046 |
3'−5' exonuclease domain-containing protein 2 |
DMO12_10425 (213) |
|
|
1 452 728 |
|
A ->AG |
L101T |
144/250/250 |
GO593_06935/FQU82_00154 |
HTZ92_3299 |
Transcriptional regulator LldL |
DMO12_00333 (250) |
|
|
2 027 426 |
|
A ->AC |
I100Y |
113/462/462 |
GO593_09615/FQU82_00690 |
HTZ92_2784 |
Aminodeoxychorismate synthase component I |
DMO12_02013 (462) |
|
|
2 761 191 |
|
T ->TG |
L96I |
100/209/209 |
GO593_13255/FQU82_01413 |
HTZ92_2145 |
Hypothetical protein |
DMO12_03804 (209) |
|
|
3 154 380 |
|
C ->CT |
N62E |
67/181/181 |
GO593_15095/FQU82_1785 |
HTZ92_1775 |
Acyltransferase |
DMO12_04716 (181) |
|
|
3 271 196 |
|
T ->TG |
R380Q |
381/576/576 |
GO593_15665/FQU82_01898 |
HTZ92_1663 |
Dipeptide ABC transporter ATP-binding protein |
DMO12_05028 (576) |
|
|
3 974 985 |
|
T ->TC |
F157I |
172/212/212 |
GO593_18930/FQU82_02556 |
HTZ92_1005 |
TetR family transcriptional regulator |
DMO12_07332 (212) |
|
|
3 976 370 |
|
G ->GA |
E45R |
75/300/300 |
GO593_18945/FQU82_02559 |
HTZ92_1002 |
ATPase AAA |
DMO12_07341 (300) |
|
|
3 977 672 |
|
T ->TC* |
W9L |
19/411/411 |
GO593_18950/FQU82_02560 |
HTZ92_1001 |
Sodium/glutamate symporter gltS |
DMO12_07344 (411) |
|
|
3 978 830 |
|
A ->ATC† |
21L‡ |
20/382/382 |
GO593_18955/FQU82_02561 |
HTZ92_1000 |
Alpha-beta fold hydrolase |
DMO12_07347 (382) |
|
|
|
SNPs between ATCC 19606(M, H) and ATCC 19606(A) |
||||||||
|
Stop codon |
711 049 |
3 389 623 |
T ->A |
K337‡ |
403/345/403§ |
GO593_03295/FQU82_03219 |
HTZ92_0363 |
Methyltransferase |
DMO12_09396 (286) |
|
Aminoacid change |
261 181 |
2 939 754 |
G ->A |
G40D |
213/213/213 |
GO593_01345/FQU82_02834 |
HTZ92_0737 |
Hypothetical protein |
DMO12_08034 (213) |
|
1 149 064 |
3 827 640 |
A ->T |
V56D |
265/265/265 |
GO593_05440/FQU82_03650 |
HTZ92_3585 |
MBL fold metallo-hydrolase |
DMO12_10692 (265) |
|
|
|
1 168 711 |
3 847 287 |
A ->T |
T36S |
70/70/70 |
GO593_05520/FQU82_03666 |
HTZ92_3569 |
Hypothetical protein |
DMO12_10740 (70) |
|
|
3 331 716 |
2 029 407 |
A ->G |
V94A |
711/711/711 |
GO593_15945/FQU82_01954 |
HTZ92_1607 |
TonB-dependent siderophore receptor |
DMO12_05199 (711) |
|
Synonymous |
20 323 |
2 698 895 |
T ->C |
S117 |
475/478/478 |
GO593_00130/FQU82_02587 |
HTZ92_0978 |
M48 family metalloprotease |
DMO12_07425 (478) |
|
|
2 190 622 |
887 198 |
T ->C |
I319 |
394/394/394 |
GO593_10430/FQU82_00850 |
HTZ92_2632 |
Hypothetical protein |
DMO12_02541 (394) |
|
Intergenic |
1 184 582 |
3 863 158 |
A ->T |
– |
– |
GO593_05600-GO593_05605/FQU82_03682-FQU82_03683 |
HTZ92_3552-HTZ92_3553 |
– |
– |
|
|
SNPs between ATCC 19606(H) and ATCC 19606(A) |
||||||||
|
Stop codon |
|
2 834 189 |
T ->A |
117L‡ |
178/117/178 |
GO593_00915/FQU82_02747 |
HTZ92_0820 |
Peptidase C39 |
DMO12_07686 (178) |
|
Aminoacid change |
|
2 573 642 |
C ->A |
R190L |
201/201/201 |
GO593_18455/FQU82_02459 |
HTZ92_1102 |
Potassium-transporting ATPase C chain |
DMO12_07086 (201) |
|
Synonymous |
|
3 278 427 |
C ->T |
R362|| |
549/549/533¶ |
GO593_02765/FQU82_03113 |
HTZ92_0463 |
Lipid A phosphoethanolamine transferase |
DMO12_09075 (533) |
*Only the first nucleotide change is shown: GO593_18950 contains ten insertions and two SNPs.
†Only the first nucleotide change is shown: GO593_18955 contains 11 insertions.
‡Indicates a stop codon.
§The predicted ORF in ATCC 19606(A) starts 27 nucleotides upstream, relative to ATCC 19606(M) and ATCC 19606(H).
||Only the first nucleotide change is shown: FQU82_03113 contains ten SNPs.
¶The predicted ORF in ATCC 19606(A) starts 48 nucleotides downstream, relative to ATCC 19606(M) and ATCC 19606(H).